Therapeutic potential of adipose tissue
نویسندگان
چکیده
منابع مشابه
Brown adipose tissue biology and therapeutic potential
BROWN ADIPOSE TISSUE Brown adipose tissue (BAT) (Figure 1) has been recognized as a key thermogenic tissue in rodents for several decades. However, in the last few years, there has been a resurgent interest in the biology and therapeutic potential of BAT. This has been largely driven by a new understanding that most, if not all, healthy adult humans have significant deposits of BAT which can be...
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Obesity is a significant health challenge, with the latest projections estimating that there will be 2.16 billion overweight and 1.12 billion obese individuals globally by 2030. In addition to social stigmatization and impaired quality of life, obese people are faced with significantly increased risk of cardiovascular disease, type 2 diabetes mellitus, and a number of cancers. Weight gain resul...
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Brown adipose tissue (BAT), an important endocrine organ long known for thermogenesis and energy consumption, has received much attention in recent years for its potential to combat obesity. In general, BAT can enhance metabolism and improve overall health. Our recent work demonstrates the ability of embryonic BAT transplants to correct type 1 diabetes (T1D) without insulin, via mechanisms some...
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Membrane potentials were recorded in isolated segments of interscapular brown adipose tissue from rats. After equilibration at 29 degrees C in Krebs-Ringer bicarbonate buffer a mean value of -51 +/- 4 mv (SD) was found. This level could be maintained for up to 5 hr. The mean effective membrane resistance was 1.35 +/- 0.45 megohm. The membrane potential was a function of the extracellular potass...
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ژورنال
عنوان ژورنال: Science Bulletin
سال: 2020
ISSN: 2095-9273
DOI: 10.1016/j.scib.2020.06.037